Carboxylic acid esters

Organic compounds that are directly derived from carboxylic acid, and contain an ester functional group substitution; ester groups contain an oxygen atom that is bonded to two carbon atoms or organic groups via single bonds.

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946 – 960 of 1,431 results

946

Medchemexpress LLC NB-598 Maleate | 155294-62-5 | 99.4% | 565.74 | 1 ML

NB-598 Maleate | 155294-62-5 | 99.4% | 565.74 | 1 ML

Pricing & Availability

947

Medchemexpress LLC Enalapril maleate | 76095-16-4 | 100.0% | 1 ML

Enalapril maleate is an active metabolite of enalapril and a potent angiotensin-converting enzyme (ACE) inhibitor. As a prodrug, it is rapidly metabolized to enalaprilat, which helps regulate blood pressure by targeting the renin-angiotensin-aldosterone system (RAAS). It is used in the treatment of essential or renovascular hypertension and symptomatic congestive heart failure.

Active metabolite of enalapril
Angiotensin-converting enzyme (ACE) inhibitor
Prodrug that converts to enalaprilat
Potent and competitive ACE inhibitor
Used to treat hypertension
Used to treat congestive heart failure

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948

Polysciences, Inc. 2-Hydroxyethyl methacrylate, Ophthalmic Grade

2-Hydroxyethyl methacrylate (HEMA) is perhaps the most widely studied and used neutral hydrophilic monomer. The monomer is soluble, its homopolymer is water-insoluble but plasticized and swollen in water. This monomer is the basis for many hydrogel products such as soft contact lenses, as well as polymer binders for controlled drug release, absorbants for body fluids and lubricious coatings. As a comonomer with other ester monomers, HEMA can be used to control hydrophobicity or introduce reactive sites.glycol methacrylateOpthalmic grade: Purity %=min. 99; Acid Content %=max 0.05; EGDMA content %=max 0.15; Color=30

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949

Apexbio Technology LLC Indacaterol Maleate 753498-25-8 50mg

Indacaterol Maleate (CAS 753498-25-8) is a synthetic ultra-long-acting agonist of -adrenoceptors exhibiting a pK sub i /sub value of 7 36 for these targets By selectively activating sub 2 /sub -adrenergic receptors it modulates intracellular signaling pathways that induce bronchodilation and smooth muscle relaxation Indacaterol Maleate is widely utilized in biomedical research to investigate -adrenergic signaling mechanisms pulmonary pharmacology and novel therapeutic interventions for respiratory disorders involving airway constriction

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950

Medchemexpress LLC 9(10H)-acridinone, 10-(3-aminopropyl)-3,4-dimethyl-, (2Z)-2-butenedioate (1:1) | 1204480-26-1 | 99.4% | 396.44 | 25 MG

ER-27319 (maleate), an acridone derivative, is a potent and selective SYK inhibitor. It inhibits the tyrosine phosphorylation of SYK and its activity. This compound also inhibits the release of antigen-induced allergic mediators from human and rat mast cells with an IC50 of 10 μM, making it useful for studying allergic diseases.

Potent and selective SYK inhibitor.
Inhibits tyrosine phosphorylation of SYK and its activity.
Inhibits the release of antigen-induced allergic mediators from human and rat mast cells with an IC50 of 10 μM.
Useful for study in allergic diseases.
Available in solid form, yellow to orange color.

Pricing & Availability

951

Matrix Scientific ETHYL PROPIOLATE-25G

Ethyl propiolate, 98%-25g,C5H6O2, MFCD00009184, mw 98.10,

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952

eMolecules 18305-60-7 | AstaTech | DI-TERT-BUTYL MALEATE | 0.25g | 233620211 | 26264 | 95 | MFCD23381095 | 228.288 | C12H20O4

Ambeed | N-(3-Chloropropyl)-4-(4455-tetramethyl-132-dioxaborolan-2-yl)benzamide | 1g | 714084318 | A1543861 | 2828443-90-7 | 323.620 | C16H23BClNO3

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953

Medchemexpress LLC U-99194 maleate | 234757-41-6 | MFCD01529985 | 99.2% | 393.47 g/mol | C21H31NO6 | 5 MG

U-99194 maleate is a selective dopamine D3 receptor antagonist supplied as the maleate salt for research use. It is commonly used to probe D3-mediated signaling and motor disorder models, and is offered in small, research-sized quantities with reported high purity for biochemical and pharmacological studies.

Selective dopamine D3 receptor antagonist useful for receptor pharmacology studies.
Supplied as the maleate salt for stability and handling.
High reported purity (99.2%) suitable for biochemical assays.
Available in small milligram pack sizes for preclinical research.
Characterized by molecular formula C21H31NO6 and molecular weight 393.47 g/mol.

Pricing & Availability

954

Medchemexpress LLC Diethyl maleate | 141-05-9 | MFCD00009191 | 98.1% | 172.18 g/mol | C8H12O4 | 500mg

Diethyl maleate (DEM) is an orally available effective glutathione (GSH) depletor that crosses the blood-brain barrier Diethyl maleate covalently binds irreversibly to GSH via glutathione S-transferase with an in vitro IC50 of 0 1-0 5 mM Diethyl maleate selectively depletes GSH in liver lung and brain tissues exacerbating oxidative stress and enhancing hyperbaric oxygen toxicity Diethyl maleate promotes precursor amino acid uptake and in turn promotes GSH synthesis by upregulating the activity of the cystine-glutamate transporter XO- Diethyl maleate can be used to study redox homeostasis and GSH protection mechanisms in oxidative stress-related diseases such as hyperbaric oxygen injury and metabolic diseases[1][2][3]

Pricing & Availability

955

Medchemexpress LLC Edonerpic (maleate) | 519187-97-4 | 99.8% | 407.48 | 100 MG

Edonerpic maleate is a novel neurotrophic agent that can inhibit amyloid-β peptides (Aβ). It is intended for research use only and is not sold to patients. In vitro, it preserves cortical neurons in the presence of Aβ(1-42), prevents oxidative stress-induced neuronal death, and promotes neurite outgrowth. In vivo, it ameliorates deficits in adult neurogenesis and spatial memory.

Novel neurotrophic agent
Inhibits amyloid-β peptides (Aβ)
In vitro efficacy: preserves cortical neurons
Prevents oxidative stress-induced neuronal death
Promotes neurite outgrowth
In vivo efficacy: ameliorates deficits in adult neurogenesis and spatial memory

Pricing & Availability

956

Medchemexpress LLC VTP50469 fumarate | 2169919-29-1 | 99.8% | 804.93 | 100 MG

VTP50469 fumarate is a potent, highly selective, and orally active Menin-MLL interaction inhibitor. It demonstrates potent anti-leukemia activity with a Ki of 104 pM.

Inhibits cell proliferation in MLL-r and ALL cell lines
Induces apoptosis in MLL-r B cell ALL cell lines
Causes dose-dependent differentiation in MLL-r AML cell lines
Displaces Menin from protein complexes and inhibits chromatin occupancy of MLL
Leads to changes in gene expression, differentiation, and apoptosis
Shows significant survival advantage in in vivo studies in NSG mice

Pricing & Availability

957

Medchemexpress LLC Dimethyl fumarate-d6 | 66487-95-4 | 99.9% | 150.16 | 1 MG

Dimethyl fumarate-d6 is a deuterium-labeled Dimethyl fumarate that acts as a nuclear factor (erythroid-derived)-like 2 (Nrf2) pathway activator, leading to the upregulation of antioxidant gene expression. It is intended for research use only and can be used for various analytical purposes.

Can be used as a tracer
Can be used as an internal standard for quantitative analysis by techniques such as NMR, GC-MS, or LC-MS

Pricing & Availability

958

Medchemexpress LLC Cinepazide (Maleate) | 26328-04-1 | 99.7% | C26H35N3O9 | 1 ML

Cinepazide Maleate is a piperazine derivative that acts as a weak calcium channel blocker and a potent vasodilator. It is used in research for cerebrovascular diseases, including ischemic stroke and brain infarct.

Acts as a piperazine derivative
Functions as a weak calcium channel blocker
Potent vasodilator
Useful in research for cerebrovascular diseases
Suitable for ischemic stroke studies
Applicable for brain infarct research

Pricing & Availability

959

Medchemexpress LLC Ciproxifan maleate | 184025-19-2 | C20H22N2O6 | 50 MG

Ciproxifan maleate is a potent, selective, orally bioavailable, and competitive antagonist of the histamine H3-receptor, with an IC50 of 9.2 nM. It shows low apparent affinity at other receptor subtypes and can be used for research of aging disorders and Alzheimer's disease.

Potent and selective antagonist of histamine H3-receptor
Orally bioavailable
Useful for research on aging disorders and Alzheimer's disease
Inhibits [3H]HA release from rat cerebral cortex synaptosomes
Improves accuracy in five-choice tasks in rats
Induces neocortical electroencephalogram activation in cats
Exhibits oral bioavailability in mice

Pricing & Availability

960

Medchemexpress LLC Dizocilpine maleate | 77086-22-7 | 337.37 | 50 MG

Dizocilpine maleate (MK-801 maleate) is a potent, selective, and non-competitive NMDA receptor antagonist with a Kd of 37.2 nM in rat brain membranes. It causes a progressive, long-lasting blockade of current induced by N-Me-D-Asp and can inhibit the activation of microglia induced by LPS. It is also used to induce schizophrenia models.

Potent, selective, and non-competitive NMDA receptor antagonist
Binds with NMDA receptor
Blocks N-Me-D-Asp-activated single-channel activity
Inhibits activation of microglia induced by LPS
Can be used to induce schizophrenia models

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Carboxylic acid esters

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Medchemexpress LLC NB-598 Maleate | 155294-62-5 | 99.4% | 565.74 | 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Enalapril maleate | 76095-16-4 | 100.0% | 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Polysciences, Inc. 2-Hydroxyethyl methacrylate, Ophthalmic Grade Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Apexbio Technology LLC Indacaterol Maleate 753498-25-8 50mg Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC 9(10H)-acridinone, 10-(3-aminopropyl)-3,4-dimethyl-, (2Z)-2-butenedioate (1:1) | 1204480-26-1 | 99.4% | 396.44 | 25 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC U-99194 maleate | 234757-41-6 | MFCD01529985 | 99.2% | 393.47 g/mol | C21H31NO6 | 5 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Diethyl maleate | 141-05-9 | MFCD00009191 | 98.1% | 172.18 g/mol | C8H12O4 | 500mg Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Edonerpic (maleate) | 519187-97-4 | 99.8% | 407.48 | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC VTP50469 fumarate | 2169919-29-1 | 99.8% | 804.93 | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Dimethyl fumarate-d6 | 66487-95-4 | 99.9% | 150.16 | 1 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Cinepazide (Maleate) | 26328-04-1 | 99.7% | C26H35N3O9 | 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Ciproxifan maleate | 184025-19-2 | C20H22N2O6 | 50 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Dizocilpine maleate | 77086-22-7 | 337.37 | 50 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More