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Filtered Search Results
Apexbio Technology LLC Ethynodiol diacetate 297-76-7 10mM (in 1mL DMSO)
Ethynodiol diacetate (297-76-7) is a small-molecule agonist targeting progesterone receptors It is designed to selectively bind and activate these receptors thereby modulating gene transcription pathways and influencing reproductive tissue responses Ethynodiol diacetate exerts its biological activity primarily through selective activation of progesterone receptors Based on these pharmacological properties Ethynodiol diacetate holds research potential in studies investigating hormonal regulation contraceptive mechanisms and modulation of the reproductive system
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Apexbio Technology LLC CA 074 134448-10-5 1mg
CA 074 (CAS 134448-10-5) is a selective inhibitor of cathepsin B a cysteine protease involved in diverse pathological mechanisms By targeting cathepsin B CA 074 alleviates neurotoxicity induced by amyloid-activated microglia and inhibits proteolytic cascades associated with cell growth suppression and plasminogen activation Additionally CA 074 treatment modulates immune responses by shifting CD4 T cells from a Th2 to a Th1 phenotype reducing IgE and IgG1 levels In vivo studies indicate that CA 074 can attenuate TNF- -induced hepatic injury highlighting its relevance as a research tool in inflammation immunology and neurodegenerative disease investigations
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Aobchem 2-Isopropenyl-4 4 5 5-tetramethyl-1 3 2-dioxaborolane | ≥97% | CAS 126726-62-3 | C9H17BO2 | 100g
2-Isopropenyl-4 4 5 5-tetramethyl-1 3 2-dioxaborolane | ≥97% | CAS 126726-62-3 | C9H17BO2 | 100g
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Eagle Biosciences Inc Tau-381 1N3R Wild-Type Monomer, 100 ug
Tau-381 (1N3R) Wild-Type Monomers
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eMolecules 36679-81-9 | 4-Hydroxymethyl-dihydro-furan-2-one | J & W PharmLab LLC | MFCD21099409 | 116.116 | C5H8O3 | 96.000 | OCC1COC(=O)C1 | 1g | 309209384
4-Hydroxymethyl-dihydro-furan-2-one | J & W PharmLab LLC | 36679-81-9 | MFCD21099409 | 116.116 | C5H8O3 | 96.000 | OCC1COC(=O)C1 | 1g | 309209384
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Medchemexpress LLC Decursinol angelate | 130848-06-5 | MFCD06796687 | 99.9% | 328.36 g/mol | C19H20O5 | 10 MG
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Decursinol angelate is a natural coumarin derivative isolated from the root of Angelica gigas. It functions as a protein kinase C (PKC) activator and has reported cytotoxic, anti-tumor, and anti-inflammatory activities. The compound is supplied as a white to off-white solid and is used in biochemical and cellular research.
- Acts as a protein kinase C (PKC) activator.
- Reported cytotoxic and anti-tumor activity in published studies.
- High reported purity suitable for analytical and biological assays.
- White to off-white solid with recommended storage at 4°C, protected from light.
- Available in small-mass sizes for laboratory experiments.
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Selleck Chemical LLC Dimethindene maleate-25MG
Dimethindene maleate is a selective antagonist of histamine H1 and exhibits antihistamine effects It suppresses the cromakalim-induced/glibenclamide-sensitive K currents in a concentration-dependent and reversible manner
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Pfaltz & Bauer n-Hexyl methacrylate| 100G | 142-09-6
n-Hexyl methacrylate| 100G | 142-09-6
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eMolecules 623-47-2 | Ethyl propiolate | Combi-Blocks | MFCD00009184 | 98.101 | C5H6O2 | 98.000 | CCOC(=O)C#C | 25g | 249355929
Ethyl propiolate | Combi-Blocks | 623-47-2 | MFCD00009184 | 98.101 | C5H6O2 | 98.000 | CCOC(=O)C#C | 25g | 249355929
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Apexbio Technology LLC (+)-MK 801 Maleate 77086-22-7 10mM (in 1mL DMSO)
( )-MK 801 Maleate is a non-competitive antagonist of the N-methyl-D-aspartate (NMDA) receptor exhibiting a Ki value of approximately 30 5 nM By blocking the NMDA receptor-mediated ion channel MK 801 disrupts glutamate-associated excitatory neurotransmission In experimental models MK 801 demonstrates anticonvulsant and anxiolytic properties through modulation of NMDA receptor activity This compound readily penetrates the central nervous system binding reversibly and region-specifically to cortical and hippocampal membranes MK 801 effectively inhibits NMDA-triggered depolarization responses in neuronal preparations making it applicable in studies focused on epilepsy excitotoxicity and neuronal signaling pathways
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Medchemexpress LLC Perhexiline (maleate) | 6724-53-4 | 100.0% | 1 ML
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Perhexiline maleate is an orally active CPT1 and CPT2 inhibitor that reduces fatty acid metabolism. It induces mitochondrial dysfunction and apoptosis in hepatic cells. It can cross the blood-brain barrier (BBB) and exhibits anti-tumor activity. Perhexiline maleate is used in the research of cancers and cardiovascular diseases like angina.
- Orally active CPT1 and CPT2 inhibitor
- Reduces fatty acid metabolism
- Induces mitochondrial dysfunction and apoptosis in hepatic cells
- Can cross the blood-brain barrier (BBB)
- Shows anti-tumor activity
- Useful in research for cancers and cardiovascular diseases like angina
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Medchemexpress LLC Perhexiline (maleate) | 6724-53-4 | 100 MG
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Perhexiline maleate is an orally active CPT1 and CPT2 inhibitor that reduces fatty acid metabolism. It induces mitochondrial dysfunction and apoptosis in hepatic cells. It can cross the blood brain barrier (BBB) and shows anti-tumor activity. It can be used in the research of cancers, and cardiovascular diseases like angina.
- Reduces fatty acid metabolism
- Induces mitochondrial dysfunction and apoptosis in hepatic cells
- Can cross the blood-brain barrier
- Exhibits anti-tumor activity
- Suitable for research in cancers and cardiovascular diseases like angina
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Apexbio Technology LLC NB-598 Maleate 155294-62-5 5mg
NB-598 Maleate is a small-molecule inhibitor targeting squalene epoxidase (SE) an essential enzyme in cholesterol biosynthesis It is designed to inhibit SE thereby disrupting the oxygenation of squalene and affecting downstream synthesis of cholesterol intermediates particularly within farnesol-dependent pathways leading to triglyceride biosynthesis NB-598 Maleate exerts its biological activity primarily through inhibition of squalene epoxidase In mouse pancreatic islet models NB-598 Maleate reduces insulin secretion under both basal and glucose-stimulated conditions Additionally this compound inhibits calcium voltage-dependent (CaV) ion channels in cellular assays Based on these pharmacological properties NB-598 Maleate holds research potential in studying cholesterol biosynthesis pathways lipid metabolism insulin regulation and the physiological role of CaV channels
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Medchemexpress LLC Way-100635 maleate | 1092679-51-0 | MFCD01321056 | 99.6% | 538.64 g/mol | C29H38N4O6 | 10 MG
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WAY-100635 maleate is the maleate salt of WAY-100635, a potent and selective 5-hydroxytryptamine 1A (5-HT1A) receptor antagonist supplied for research use in in vitro and in vivo pharmacology studies.
- Potent 5-HT1A receptor antagonist (IC50 0.91 nM; Ki 0.39 nM)
- High purity (≈99.6%) suitable for analytical and pharmacological studies
- Molecular weight 538.64 g/mol; formula C29H38N4O6
- Available in small pack sizes for research, including 10 mg
- For research use only; not for human or veterinary use
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Medchemexpress LLC Cipralisant maleate | 223420-20-0 | 99.8% | 332.39 g·mol-1 | C18H24N2O4 | 10 MG
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Cipralisant maleate is a research-grade histamine H3 receptor antagonist supplied as the maleate salt. It is used in pharmacology and neuroscience studies to probe H3 receptor activity and related signaling pathways. Provided as a solid with high reported purity, this compound is for laboratory research use only and not for human or veterinary applications.
- Orally active histamine H3 receptor antagonist for research applications.
- High purity (99.8%).
- White to off-white solid appearance.
- Soluble in DMSO (≥ 100 mg/mL).
- Molecular weight 332.39 g·mol-1; formula C18H24N2O4.
- Stable as powder at -20°C for long-term storage; in solution store at -80°C.
- Supplied in small laboratory-scale quantities suitable for preclinical studies.
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